Uveitis in association with multiple sclerosis.

نویسنده

R Porter

چکیده

Rucker (I944) was first to describe sheathing of retinal veins in patients with multiple sclerosis. This was supported by later observers (Treusch and Rucker, 1944; Haar, I953; Scott, I96I), but the incidence was found to vary from IO to 23 per cent. It was initially thought that this periphlebitis was not associated with other ocular conditions, and might indicate a possible pathological basis for multiple sclerosis, with areas of periphlebitis scattered throughout the central nervous system. Later reports, however, demonstrated an association between this retinal vein sheathing and a posterior uveitis in similar patients (Archambeau, Hollenhorst, and Rucker, I965), and more recently an association has been demonstrated between multiple sclerosis and the clinical entity of peripheral uveitis (pars planitis) (Breger and Leopold, I966; Giles, I970), which may include sheathing of the retinal veins (Brockhurst, Schepens, and Okamura, i 960). Other workers have failed to confirm these findings and feel that retinal sheathing represents a retinal light reflex (Field and Foster, I962). More recently other observers have failed to find any significant incidence of either retinal vein sheathing or uveitis in patients with multiple sclerosis (Lossner, Muller, and Bachman, I968). In view of these conflicting reports, and the persistent similarities between the latest theories concerning the aetiologies of both uveitis and multiple sclerosis, it was considered worthwhile to carry out a new ocular survey of patients with multiple sclerosis.

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